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WEDNESDAY, 7 NOVEMBER 2018
- 09:00 – 16.30
- PRE-CONFERENCE COURSE
(separate registration required) - HANDS ON COMPUTATIONAL COURSE
Objectives: To overview and conquer selected state-of-the-art computational approaches and available software for dynamical and statistical modelling and apply these in research and healthcare
• How to construct and analyze biological networks
• How to find and/or overcome the missing data
• To find the interactions among the modelling, the wet-lab and the clinics - 09:00 – 09:15
- Computational modelling from life science perspective – introduction
Prof. Dr. Damjana Rozman, Centre for Functional Genomics and Bio-chips, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia - 09:15 – 10:45
- Large scale computational modelling of complex liver metabolism: object oriented perspective – hands on tutorial
Dr. Miha Moškon, Faculty of Computer and Information Science, University of Ljubljana
Dr. Tanja Cvitanović Tomaš, Centre for Functional Genomics and Bio-chips, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia - 11:00 – 12:30
- Networks and Machine learning in Medicine – hands on tutorial
Dr. Tavpritesh Sethi, Indraprastha Institute of Information Technology, Delhi, India - 12:30 – 13:30
- LUNCH
- Computational modeling for clinicians – taking big data in clinical decision making
Objectives: To share a vision into the future of big data in clinical decision making, and an overview of new technologies for communicating with colleagues and patients.
• What would change the world for a patient?
• How to bring big data in daily clinical care
• What, and how fast, is this technology coming to clinical practice. - 13:30 – 14.30
- Molecular classification of disease – an introduction to a new way of thinking in medicine
Prof. Dr. T.R.D.J. Radstake, University Medical Center Utrecht, The Netherlands - 14.30 – 15.30
- Computational modeling for clinicians – getting useful clinical decisions out of big data
Dr. Aridaman Pandit, University Medical Center Utrecht, The Netherlands - 15.30 – 16.30
- Epigenomic signatures as prognostic biomarkers in rheumatoid arthritis
Prof. Dr. Carl Goodyear, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom - 15.30 – 17.30
- REGISTRATION
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SESSION I.
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OFFICIAL OPENING
- 17.30 – 18.00
- OFFICIAL OPENING
Pressing of the official coin of the 2nd International meeting on Systems Medicine
& opening of the meeting
Prof. Dr. Timothy R.D.J. Radstake (Vice Chair EASyM & Chair Scientific Committee) - 18.00 – 18.30
- 1st Keynote speech: EU actions to advance personalised medicine
Irene Norstedt, Personalised Medicine Unit in DG Research and Innovation, European Commission - 18.30 – 19.00
- 2nd Keynote speech: Systems Vaccinology
Prof. Dr. Bali Pulendran, Departments of Pathology and of Microbiology & Immunology, Stanford University School of Medicine, USA - 19.30 – 20.00
- The newest challenge in research – facing the General Data Protection Regulations
David Supple, Expert in GDPR compliance, Privacy Consultant, Zissou Projects ltd - 20.00 – 21.30
- OPENING RECEPTION
The opening reception will be held in the historical atmosphere of the conference venue “Muntgebouw”. Guided tours through the magnificent building will be offered. Enjoy the evening overlooking the monumental facade of the building and fire baskets through the glass wall from the room where the first coins are pressed. -
THURSDAY, 8 NOVEMBER 2018
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SESSION II.
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WHAT TO DO WITH THE BUGS – KILL THEM OR EAT THEM
Chairs: Prof. Dr. Aletta D. Kraneveld, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences of Utrecht University, The Netherlands & Prof. Dr. John F. Cryan, University College Cork, Ireland
- 09.00 – 09.30
- How mucosal immunity can steer joint inflammation in SpA: a translational medicine approach
Prof. Dr. Dirk Elewaut, Unit Molecular Immunology and Inflammation, VIB Inflammation Research Center, Ghent University, Belgium and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium - 09.30 – 10.00
- Microbiome-gut-brain axis
Prof. Dr. John Cryan from UC Cork/Microbiome Institute, Ireland - 10.00 – 10.30
- Gut-lung axis (early life & intestinal bugs in allergy)
Prof. Dr. Jeroen Raes, VIB-KU Leuven, Belgium - 10.30 – 10.45
- Abstract
- 10.45 – 11.00
- Break
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SESSION III.
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HOW TO BRING BIG DATA INTO CLINICAL CARE – PRACTICAL IMPLICATIONS
Chair: Prof. Dr. Harald Schmidt, Dept. of Pharmacology and Personalised Medicine, Maastricht University, The Netherlands & David Gomez-Cabrero, King’s College London Dental Institute & Karolinska Institutet
- 11.00 – 11.15
- Abstract
- 11.15 – 11.30
- Abstract
- 11.30 – 12.00
- iKNIFE
Prof. Dr. Ron M.A. Heeren, University of Maastricht, The Netherlands - 12.00 – 12.30
- Severe asthma fingerprints: from discovery to point of care (U-BIOPRED)
Prof. Dr. Peter J. Sterk, Academic Medical Center, Amsterdam, The Netherlands - 12.30 – 13.30
- Lunch & posters
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SESSION IV.
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SYSTEMS MEDICINE; FROM THE BEGINNING TO THE END
Chairs: Prof. Dr. Marta Cascante, Dept. Biochemistry and Molecular Biology, Faculty of Biology, Universitat de Barcelona, Spain & Prof. Dr. Werner Müller, Faculty of Life Science, University of Manchester, United Kingdom
- 13.30 – 14.00
- Dendritic cells in health and disease
Prof. Dr. Florent Ginhoux, Singapore University, Singapore - 14.00 – 14.30
- Dissecting disease and treatment endotypes by pathobiology in rheumatoid arthritis: towards precision medicine
Prof. Dr. Costantino Pitzalis, Director Arthritis Research UK Experimental Arthritis Treatment Centre, William Harvey Research Institute, Queen Mary University of London, United Kingdom - 14.30 – 15.00
- From diagnosis to molecular stratification in multiple inflammatory diseases
Speaker tbc - 15.00 – 15.30
- Break
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SESSION V.
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INDUSTRY-SPONSORED SYMPOSIUM
- 15.30 – 16.30
- Click here for details
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SESSION VI.
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THE EXPOSOME AND SYSTEMS HEALTH
- 16.45 – 17.15
- Computational Gastronomy: An emerging data science of food, flavors and health
Dr. Ganesh Bagler, CSIR-Centre for Cellular and Molecular Biology, Delhi, India - 17.15 – 17.45
- The Exposome: System-atically connecting the Environmental to Health
Prof. Dr. Ir. Roel Vermeulen, Professor of Environmental Epidemiology and Exposome Science | Utrecht University & Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands - 17.45 – 18.45
- General Assembly EASyM
- 19.30 – 23.00
- GALA DINNER at the UNIVERSITY HALL (tickets available for € 50)
The Gala Dinner will take place at the monumental University Hall in the centre of the city. It is Utrecht University’s ceremonial heart and public face. -
FRIDAY, 9 NOVEMBER 2018
- 9.00 – 10.00
- Guided poster tours
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SESSION VII.
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FROM PATIENT STRATIFICATION TO NOVEL DISEASE CLASSIFICATIONS (TAXONOMY). SOME RECENT EXAMPLES
Chairs: Prof. Dr. Anke-Hilse Maitland, Faculty of Medicine, University of Amsterdam, The Netherlands & Prof. Dr. Andre Franke, Faculty of medicine, University of Kiel, Germany
- 10.00 – 10.20
- Molecular handprints in asthma and how to translate to clinical care
Åsa Wheelock, Karolinska University Hospital, Stockholm, Sweden - 10.20 – 10.40
- The risk of marker panels
Dr. Jan Baumbach, Max Planck Institute, Saarbrucken, Germany - 10.40 – 11.00
- From molecular profiling to precision medicine in pancreatic cancer
Dr. David K. Chang, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, United Kingdom - 11.00 – 11.20
- Systems modelling of cell death pathways to explain glioblastoma resistance
Prof. Dr. Jochen Prehn, Centre for Systems Medicine, Royal College of Surgeons (RCSI), Dublin, Ireland - 11.20 – 11.30
- Discussions
- 11.30 – 11.50
- Break
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SESSION VIII.
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BIG DATA FROM AND FOR THE PATIENT
- 11.50 – 12.20
- Whose data is it anyway? Embedding the patient perspective in EULAR’s policy work on research and healthcare
Neil Betteridge, international liaison officer, public affairs, for EULAR - 12.20 – 12.40
- Exploring the exposome: a new paradigm on using patient data
Dr. Tjitske Bezema, Founder Immunowell, The Netherlands - 12.40 – 13.00
- Patient data: a family physician’s point of view
Prof. Dr. Igor Švab, Faculty of Medicine, University of Ljubljana, Slovenia - 13.00 – 13.30
- Lunch, Awards, Prizes
- 13.30 – 14.15
- Closing keynote lecture
Speaker tbd - 14.15
- Closing of conference
Prof. Dr. Charles Auffray - 14.30
- Adjourn
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